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Fact Sheet: Ventilation and Air Quality in Offices

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Millions of Americans work in buildings with mechanical heating, ventilation, and air-conditioning (HVAC) systems; these systems are designed to provide air at comfortable temperature and humidity levels, free of harmful concentrations of air pollutants. While heating and air-conditioning are relatively straightforward operations, the more complex processes involved in ventilation are the most important in determining the quality of our indoor air.

http://www.epa.gov/iedweb00/pubs/ventilat.html